Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.1
USERS' SCORE
Good
Based on 10 Reviews
8.2
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin E (as D-alpha tocopheryl succinate)
20.1 mg
134%
Selenium (as Se-Methyl L-Selenocysteine, L-selenomethionine (yeast-free), sodium selenite)
200 mcg
364%

Top Medical Research Studies

9
Vitamin E reduces menstrual pain
We investigated whether vitamin E could help with primary dysmenorrhea, a common cause of pelvic pain for young women. In our study, 278 girls aged 15-17 took either vitamin E or a placebo before and during their menstrual periods.

Results showed that those taking vitamin E experienced significantly less pain and shorter pain duration compared to the placebo group. There was also a notable reduction in menstrual blood loss. This suggests that vitamin E may be a beneficial option for managing menstrual discomfort.
Read More
8
Vitamin E may reduce dysmenorrhea pain
In a double-blind clinical trial, we examined the impact of vitamin E on pelvic pain for 120 women suffering from primary dysmenorrhea. Participants were divided into two groups, with one receiving daily doses of 400 IU of vitamin E, while the other group received a placebo.

Our findings showed that both groups reported reduced pain; however, those taking vitamin E experienced a more significant drop in pain severity. This indicates that vitamin E could be a safe and effective option for treating menstrual pain in women.
Read More
8
Vitamin E offers menstrual pain relief
We explored how effective vitamin E is in treating primary dysmenorrhoea through a randomized placebo-controlled trial. In this study, 100 girls aged 16-18 were divided into two groups; one received 500 units of vitamin E daily, while the other took a placebo.

Treatment started two days before menstruation and continued for three days. Both groups experienced relief from pain, but those taking vitamin E reported more significant improvements.

This suggests that while both treatments help, vitamin E may offer an added benefit in managing menstrual pain.
Read More

Most Useful Reviews

9
Thyroid discomfort relief
2 people found this helpful
I consistently alternate between different brands, and a dosage of 200 is perfect. Although it's advised not to take selenium constantly, I've noticed my eyes have returned to normal, and the heaviness, pain, and pressure in my thyroid at night have subsided.
Read More
9
Mood boost
1 people found this helpful
After two weeks on the super selenium complex, I noticed a reduction in hair loss and an uplift in my mood. Additionally, the spontaneous pains in my chest and thyroid region have vanished.
Read More
9
Rapid pain relief
15 people found this helpful
This product was recommended on a thyroid forum. While it's early to determine its full benefits, I believe I may have experienced some. A week ago, I suffered from severe pain due to a fallen arch on my right foot. As this can be linked to low thyroid function, I decided to try this supplement. After just two days of wearing supportive insoles and taking selenium, my foot pain disappeared completely! The pain was once excruciating, prompting a visit to A&E. I was astonished to find I had no pain at all two days later. I hope selenium contributed to this swift recovery.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.1
  • All Researches
9
Vitamin C and E reduce pelvic pain
We examined the effects of vitamin C and E on pelvic pain in women with endometriosis through a triple-blind, placebo-controlled trial. Sixty women aged 15-45 participated, receiving either the vitamin combination or a placebo daily for eight weeks.

Our results revealed noteworthy decreases in pelvic pain, dysmenorrhea, and dyspareunia for those who took vitamins, supporting their potential in managing endometriosis symptoms. While oxidative stress markers showed changes, total antioxidant capacity did not significantly decline.
Read More
9
Vitamin E reduces menstrual pain
We investigated whether vitamin E could help with primary dysmenorrhea, a common cause of pelvic pain for young women. In our study, 278 girls aged 15-17 took either vitamin E or a placebo before and during their menstrual periods.

Results showed that those taking vitamin E experienced significantly less pain and shorter pain duration compared to the placebo group. There was also a notable reduction in menstrual blood loss. This suggests that vitamin E may be a beneficial option for managing menstrual discomfort.
Read More
8
Multimodal therapy improves pelvic pain
We examined the potential of a multimodal therapy approach for treating chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using the UPOINTS phenotyping system. Involving 914 patients, the study combined α-blockers, supplements like selenium, and antibacterial agents among others.

After a six-month course, we noted significant improvements in symptoms, with 77.5% of patients achieving a meaningful reduction in their pain scores. Notably, patients with the inflammatory subtype showed marked symptom relief compared to the non-inflammatory group. This suggests a tailored approach could effectively address the complexities of CP/CPPS.
Read More
8
Selenium enhances pelvic pain treatment
We evaluated the effects of a treatment combining Serenoa repens with selenium and lycopene, known as Profluss, against Serenoa repens alone for chronic pelvic pain in 102 men. After an 8-week period, both groups experienced symptom improvements. However, the Profluss group showed a significantly greater reduction in pelvic pain scores and additional benefits in other measures, suggesting that selenium can enhance treatment effectiveness for this condition.

While both treatments offered relief, Profluss was particularly beneficial. This finding indicates that adding selenium to standard therapy might be advantageous in managing pelvic pain.
Read More
8
Vitamin E supports pelvic pain relief
We explored the impact of antioxidants, specifically vitamins C and E, on pelvic pain associated with endometriosis. Analyzing data from five randomized controlled trials, we found that patients receiving vitamin supplementation reported significant reductions in chronic pelvic pain, dysmenorrhea, and dyspareunia compared to those on placebo.

This suggests that these vitamins may play a beneficial role in alleviating symptoms for those suffering from endometriosis-related pain. Overall, antioxidant supplementation presents a promising avenue for management of this challenging condition.
Read More

User Reviews

USERS' SCORE
Good
Based on 10 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Thyroid discomfort relief
2 people found this helpful
I consistently alternate between different brands, and a dosage of 200 is perfect. Although it's advised not to take selenium constantly, I've noticed my eyes have returned to normal, and the heaviness, pain, and pressure in my thyroid at night have subsided.
Read More
9
Mood boost
1 people found this helpful
After two weeks on the super selenium complex, I noticed a reduction in hair loss and an uplift in my mood. Additionally, the spontaneous pains in my chest and thyroid region have vanished.
Read More
9
Rapid pain relief
15 people found this helpful
This product was recommended on a thyroid forum. While it's early to determine its full benefits, I believe I may have experienced some. A week ago, I suffered from severe pain due to a fallen arch on my right foot. As this can be linked to low thyroid function, I decided to try this supplement. After just two days of wearing supportive insoles and taking selenium, my foot pain disappeared completely! The pain was once excruciating, prompting a visit to A&E. I was astonished to find I had no pain at all two days later. I hope selenium contributed to this swift recovery.
Read More
9
Back pain reduction
1 people found this helpful
This selenium with Vitamin E supplement is the best I've chosen among many magnesium options. After regular use, my body has improved significantly; my back pain has decreased enormously, and I feel more energetic. I no longer feel hollowed out and sleep better at night, making this a truly excellent product.
Read More
7.5
Less neck pain
1 people found this helpful
Great for proper TSH and T4 function, selenium boosts immunity while protecting the thyroid. I noticed improvements in my TSH and T4 levels while taking this complex, even if Hashimoto's antibody levels only dropped slightly. It's an excellent alternative to hormonal drugs when thyroid function is poor. I feel energised, with less pain in my neck, and plan to take it alone in the morning for better absorption, aided by vitamin E.
Read More

Frequently Asked Questions

9
Rapid pain relief
15 people found this helpful
This product was recommended on a thyroid forum. While it's early to determine its full benefits, I believe I may have experienced some. A week ago, I suffered from severe pain due to a fallen arch on my right foot. As this can be linked to low thyroid function, I decided to try this supplement. After just two days of wearing supportive insoles and taking selenium, my foot pain disappeared completely! The pain was once excruciating, prompting a visit to A&E. I was astonished to find I had no pain at all two days later. I hope selenium contributed to this swift recovery.
9
Mood boost
1 people found this helpful
After two weeks on the super selenium complex, I noticed a reduction in hair loss and an uplift in my mood. Additionally, the spontaneous pains in my chest and thyroid region have vanished.
7.5
Overall health improvement
For those dealing with hypothyroidism, this yeast-free selenium in a highly digestible form is vital. Paired with vitamin E, it significantly helps combat autoimmune thyroid conditions. I've been following a regimen of two months on and one month off, and I've experienced less muscle pain and better overall health as selenium lowers antibody levels and enhances my wellbeing.
9
Back pain reduction
1 people found this helpful
This selenium with Vitamin E supplement is the best I've chosen among many magnesium options. After regular use, my body has improved significantly; my back pain has decreased enormously, and I feel more energetic. I no longer feel hollowed out and sleep better at night, making this a truly excellent product.
7.5
Menstrual pain relief
1 people found this helpful
This wonderful complex for women was suggested by a renowned blogger. I was amazed by the visible effects: my lips and palms stopped cracking and drying up, and the pain during my menstrual cycle lessened. Selenium is vital for all genders, and when paired with vitamin E, the efficacy is enhanced! I plan to continue taking it and recommend it if you are considering iodine as well, to improve absorption.
2
Digestive issues resolved
I had to stop taking this selenium VE product because it caused substantial stomach aches akin to premenstrual discomfort. Once I ceased its use, I felt fine again. My doctor explained that reactions can vary among individuals.
7.5
Menstrual discomfort relief
I always recommend women take selenium with vitamin E, particularly during menstruation, as it significantly alleviated my severe menstrual pain.
8
Multimodal therapy improves pelvic pain
We examined the potential of a multimodal therapy approach for treating chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) using the UPOINTS phenotyping system. Involving 914 patients, the study combined α-blockers, supplements like selenium, and antibacterial agents among others.

After a six-month course, we noted significant improvements in symptoms, with 77.5% of patients achieving a meaningful reduction in their pain scores. Notably, patients with the inflammatory subtype showed marked symptom relief compared to the non-inflammatory group. This suggests a tailored approach could effectively address the complexities of CP/CPPS.
We focused on the effects of a dietary supplement combining several natural ingredients, including selenium, on chronic pelvic pain in men with Category IIIA prostatitis.

Patients taking this supplement showed significant reductions in inflammation and pain, as evidenced by lower white blood cell counts in seminal fluid and improved pain scores.

These findings suggest that selenium, along with other nutrients, may play a beneficial role in alleviating pelvic pain associated with chronic prostatitis.
8
Selenium enhances pelvic pain treatment
We evaluated the effects of a treatment combining Serenoa repens with selenium and lycopene, known as Profluss, against Serenoa repens alone for chronic pelvic pain in 102 men. After an 8-week period, both groups experienced symptom improvements. However, the Profluss group showed a significantly greater reduction in pelvic pain scores and additional benefits in other measures, suggesting that selenium can enhance treatment effectiveness for this condition.

While both treatments offered relief, Profluss was particularly beneficial. This finding indicates that adding selenium to standard therapy might be advantageous in managing pelvic pain.
7
Selenium boosts antioxidant status
We sought to understand how a mineral-vitamin complex, specifically Selzinc-plus, may help treat chronic abacterial prostatitis, a condition often linked with pelvic pain. In a study involving 47 men, we divided them into two groups: one received standard therapy, and the other received additional Selzinc-plus for two months.

While standard therapy showed effects, the antioxidant treatment significantly enhanced these benefits on symptoms. Notably, though the overall antioxidant system improved, no significant changes were observed in leukocyte counts. Our findings suggest that this antioxidant approach may offer added relief for those suffering from pelvic pain.

References

  1. Shevchenko S Y, Kulchavenya E V, Baranchukova A A. [The possibility of correcting oxidative stress in patients with inflammatory type of chronic abacterial prostatitis (chronic pelvic pain syndrome category IIIa)]. Urologiia. 2023.
  2. Magri V, Marras E, Restelli A, Wagenlehner FM, Perletti G. Multimodal therapy for category III chronic prostatitis/chronic pelvic pain syndrome in UPOINTS phenotyped patients. Exp Ther Med. 2015;9:658.
  3. Lombardo F, Fiducia M, Lunghi R, Marchetti L, Palumbo A, et al. Effects of a dietary supplement on chronic pelvic pain syndrome (Category IIIA), leucocytospermia and semen parameters. Andrologia. 2012;44 Suppl 1:672. doi:10.1111/j.1439-0272.2011.01248.x
  4. Morgia G, Mucciardi G, Galì A, Madonia M, Marchese F, et al. Treatment of chronic prostatitis/chronic pelvic pain syndrome category IIIA with Serenoa repens plus selenium and lycopene (Profluss) versus S. repens alone: an Italian randomized multicenter-controlled study. Urol Int. 2010;84:400. doi:10.1159/000302716
  5. Bayu P, Wibisono JJ. Vitamin C and E antioxidant supplementation may significantly reduce pain symptoms in endometriosis: A systematic review and meta-analysis of randomized controlled trials. PLoS One. 2024;19:e0301867. doi:10.1371/journal.pone.0301867
  6. Zheng SH, Chen XX, Chen Y, Wu ZC, Chen XQ, et al. Antioxidant vitamins supplementation reduce endometriosis related pelvic pain in humans: a systematic review and meta-analysis. Reprod Biol Endocrinol. 2023;21:79. doi:10.1186/s12958-023-01126-1
  7. Alikamali M, Mohammad-Alizadeh-Charandabi S, Maghalian M, Mirghafourvand M. The effects of vitamin E on the intensity of primary dysmenorrhea: A systematic review and meta-analysis. Clin Nutr ESPEN. 2022;52:50. doi:10.1016/j.clnesp.2022.10.001
  8. Amini L, Chekini R, Nateghi MR, Haghani H, Jamialahmadi T, et al. The Effect of Combined Vitamin C and Vitamin E Supplementation on Oxidative Stress Markers in Women with Endometriosis: A Randomized, Triple-Blind Placebo-Controlled Clinical Trial. Pain Res Manag. 2021;2021:5529741. doi:10.1155/2021/5529741
  9. Orimadegun BE, Awolude OA, Agbedana EO. Markers of lipid and protein peroxidation among Nigerian university students with dysmenorrhea. Niger J Clin Pract. 2019;22:174. doi:10.4103/njcp.njcp_279_18
  10. Sadeghi N, Paknezhad F, Rashidi Nooshabadi M, Kavianpour M, Jafari Rad S, et al. Vitamin E and fish oil, separately or in combination, on treatment of primary dysmenorrhea: a double-blind, randomized clinical trial. Gynecol Endocrinol. 2018;34:804. doi:10.1080/09513590.2018.1450377
  11. Pattanittum P, Kunyanone N, Brown J, Sangkomkamhang US, Barnes J, et al. Dietary supplements for dysmenorrhoea. Cochrane Database Syst Rev. 2016;3:CD002124. doi:10.1002/14651858.CD002124.pub2
  12. Ray K, Fahrmann J, Mitchell B, Paul D, King H, et al. Oxidation-sensitive nociception involved in endometriosis-associated pain. Pain. 2015;156:528. doi:10.1097/01.j.pain.0000460321.72396.88
  13. Kashanian M, Lakeh MM, Ghasemi A, Noori S. Evaluation of the effect of vitamin E on pelvic pain reduction in women suffering from primary dysmenorrhea. J Reprod Med. 2013;58:34.
  14. Santanam N, Kavtaradze N, Murphy A, Dominguez C, Parthasarathy S. Antioxidant supplementation reduces endometriosis-related pelvic pain in humans. Transl Res. 2013;161:189. doi:10.1016/j.trsl.2012.05.001
  15. Ziaei S, Zakeri M, Kazemnejad A. A randomised controlled trial of vitamin E in the treatment of primary dysmenorrhoea. BJOG. 2005;112:466.
  16. Ziaei S, Faghihzadeh S, Sohrabvand F, Lamyian M, Emamgholy T. A randomised placebo-controlled trial to determine the effect of vitamin E in treatment of primary dysmenorrhoea. BJOG. 2001;108:1181.
  17. Kryzhanovskiĭ GN, Bakuleva LP, Luzina NL, Vinogradov VA, Iarygin KN. [Endogenous opioid system in the realization of the analgesic effect of alpha-tocopherol in reference to algomenorrhea]. Biull Eksp Biol Med. 1988;105:148.
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